Introduction: Prostate cancer is a common malignancy affecting men and the second leading cause of cancer related death in India.Numerous molecular biomarkers have been evaluated for their potential role in predicting disease progression, their response to therapy and survival.Erythroblast Transformation Specific (ETS) related Gene (ERG) is one of
Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis
Abstract Background Sepsis, a life-threatening organ dysfunction caused by a dysregulated systemic immune response to infection, associates with reduced responsiveness to subsequent infections.How such tolerance is acquired is not well understood but is known to involve epigenetic and transcriptional dysregulation.Methods Bead arrays were used to c
Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family.
Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship.Such protozoa inhabit a single invertebrate host during their entire life cycle and exhibit special characteristics that group them in a partic